Shesto 5mg, 10mg and 20mg

Shesto 5mg, 10mg and 20mg

Escitalopram Oxalate Tablets I.P.

Shesto (Escitalopram Oxalate Tablets I.P.) contains the SSRI salt escitalopram oxalate, the active S-enantiomer of citalopram. Depression and anxiety disorders are linked to reduced serotonin signaling in brain circuits that regulate mood, worry, sleep, and concentration. Escitalopram selectively blocks the serotonin transporter (SERT), increasing serotonin availability at the synapse and gradually restoring balance in these circuits. Compared with many older antidepressants, SSRIs like escitalopram have minimal anticholinergic or cardiac effects at usual doses and are generally well tolerated. Early improvements in sleep, energy, and anxiety can appear in one to two weeks, with full benefit typically developing over four to six weeks of regular dosing.

Shesto (escitalopram oxalate) is prescribed for major depressive disorder and generalized anxiety disorder. Based on a clinician’s judgment and local guidance, it may also be used for panic disorder, social anxiety disorder, obsessive–compulsive disorder, and post-traumatic stress disorder when an SSRI is appropriate.

Your prescriber chooses among the three strengths to match your needs and sensitivity. Shesto-5 mg offers a gentle start, commonly used in anxiety disorders or in patients prone to side effects; the dose may be increased after about a week. Shesto-10 mg is the usual adult starting and maintenance dose for depression and many anxiety conditions. If symptoms persist and the medicine is well tolerated, the dose may be raised to Shesto-20 mg once daily, which is the typical maximum. Take the tablet once daily, morning or evening, at the same time each day, with a glass of water. Elderly patients and those with liver impairment generally start lower and titrate more slowly; dose adjustment is usually not required in kidney disease, but clinical judgment applies. Do not stop suddenly unless your doctor advises, as tapering helps avoid discontinuation symptoms such as dizziness, “electric-shock” sensations, irritability, and sleep disturbance.

Storage: Store Shesto in a cool, dry place away from moisture and direct sunlight, and keep the pack out of the reach of children.

Common Side Effects: Escitalopram is generally well tolerated. Some people experience nausea, loose stools or dry mouth, headache, insomnia or sleepiness, dizziness, sweating, tremor, and changes in sexual function (reduced desire, delayed orgasm). Appetite or weight may change slightly. Seek medical help promptly for unusual bruising or bleeding, severe agitation, eye pain with visual changes, rash or hives, or any thoughts of self-harm.

Drug Warnings: Before taking Shesto (escitalopram oxalate), inform your doctor if you have bipolar disorder or a history of mania/hypomania, seizures, glaucoma (especially narrow-angle), liver disease, low sodium or use of diuretics, bleeding problems or use of blood thinners, heart-rhythm issues or a family history of long QT, or if you are pregnant, planning pregnancy, or breastfeeding. Avoid taking this medicine with other sedating medications unless advised, as it may increase drowsiness.

Drug–Drug Interactions: Shesto must not be used with monoamine oxidase inhibitors (MAOIs), including linezolid or methylene blue, or within 14 days of stopping an MAOI, due to the risk of serotonin syndrome. Combining with other serotonergic agents—for example other SSRIs/SNRIs, triptans, tramadol, lithium, or St John’s wort—increases the serotonin-syndrome risk and needs medical supervision. Escitalopram can raise bleeding tendency with aspirin, NSAIDs, or anticoagulants such as warfarin. As a CYP2D6 inhibitor, it may increase levels of some medicines (certain TCAs, antipsychotics, and metoprolol); dose adjustments may be required. Use caution with drugs that prolong QT (specific antiarrhythmics, some macrolides/fluoroquinolones, certain antipsychotics). Always tell your doctor about all prescription medicines, over-the-counter drugs, and herbal supplements you are taking.

Drug–Food Interactions: Shesto can be taken with or without food. Limit alcohol, as it may worsen sleepiness, dizziness, or judgment. There are no routine dietary restrictions for the tablet.

Drug–Disease Interactions: Patients with liver impairment need lower doses and careful monitoring. Caution is advised in those with bipolar disorder, seizure disorders, hyponatremia/SIADH risk, glaucoma, or cardiac arrhythmias/long QT. Always share your full medical history to ensure the safe and effective use of Shesto-5 mg, Shesto-10 mg, and Shesto-20 mg (escitalopram oxalate).