Ramditic DT 50mg and 100mg

Ramditic DT 50mg and 100mg

Lamotrigine Dispersible Tablets IP

Ramditic DT 50mg and 100mg (Lamotrigine Dispersible Tablets IP) contains the anticonvulsant salt lamotrigine in a dispersible/chewable form. Seizures and some mood episodes are linked to excessive, rapid firing of neurons and increased release of excitatory neurotransmitters such as glutamate. Lamotrigine stabilizes neuronal membranes by blocking voltage-sensitive sodium channels and reducing pathologic glutamate release. This helps prevent partial-onset and generalized seizures, improves seizure control in Lennox–Gastaut syndrome, and in bipolar disorder helps maintain mood stability and delay new depressive or manic episodes. Because Ramditic DT tablets disperse in water or can be chewed, they are convenient for people who have difficulty swallowing solid tablets.

Ramditic DT (lamotrigine) is used under medical supervision for epilepsy, including partial-onset seizures, primary generalized tonic–clonic seizures, and seizures associated with Lennox–Gastaut syndrome, either alone or with other antiepileptic medicines. In adults with bipolar I disorder, lamotrigine is prescribed for maintenance treatment to delay the time to occurrence of mood episodes, particularly depression. Any other use should be guided by your clinician.

Lamotrigine requires slow, stepwise titration to minimize the risk of serious skin rash. Your doctor will choose a schedule based on the other medicines you take. When no valproate and no enzyme-inducing antiepileptic drugs (carbamazepine, phenytoin, phenobarbital, primidone) are present, the usual adult start is very low for 2 weeks, then increased every 1–2 weeks until the effective dose is reached. When valproate is used, doses are about half because valproate raises lamotrigine levels; when strong enzyme inducers are used, doses are higher. For bipolar maintenance, a typical target is 200 mg/day (lower with valproate, higher with inducers). Your prescriber will use the 50-mg and 100-mg Ramditic DT strengths to build the dose gradually. To take a dispersible tablet, place it on the tongue and chew, or disperse it in a small amount of water and swallow immediately; you may also swallow the tablet whole with water. Do not change your dose or stop suddenly unless your doctor tells you to; abrupt changes can increase seizure risk or trigger mood symptoms.

Storage: Store Ramditic DT in a cool, dry place away from moisture and direct sunlight. Keep out of the reach of children.

Common Side Effects: The most reported effects are dizziness, headache, sleepiness or insomnia, nausea, vomiting, blurred or double vision, lack of coordination and skin rash. Most reactions are mild and improve with time. However, a rash can rarely be severe (Stevens–Johnson syndrome/toxic epidermal necrolysis) especially in the first 2–8 weeks or when the dose is increased too quickly; stop the medicine and seek urgent care if you develop a widespread rash, mouth sores, fever or swollen glands. Very rare immune reactions (such as DRESS/HLH), blood disorders or aseptic meningitis have been reported. Seek help if you notice persistent fever, severe fatigue, unusual bruising, yellowing of the skin/eyes, stiff neck, or confusion. Like other antiepileptics, lamotrigine may increase the risk of suicidal thoughts in a small number of people; contact a clinician immediately for new or worsening mood changes.

Drug Warnings: Before taking Ramditic DT (lamotrigine), inform your doctor if you have heart rhythm problems or structural heart disease, liver or kidney disease, a history of serious drug rashes (especially to other antiepileptics), immune disorders, depression or bipolar disorder with recent mood instability, or if you are pregnant, planning pregnancy or breastfeeding. Avoid taking this medicine with other sedating medications unless advised, as it may increase drowsiness.

Drug–Drug Interactions: Lamotrigine interacts importantly with other antiepileptics. Valproate markedly increases lamotrigine levels, doses must be lower and titration slower. Carbamazepine, phenytoin, phenobarbital, primidone and rifampicin decrease lamotrigine levels higher doses may be required. Estrogen-containing oral contraceptives can reduce lamotrigine concentrations during the active-pill weeks and raise them in the pill-free week; your doctor may adjust doses and advise on monitoring. Certain HIV medicines and some antidepressants may also affect levels or add to side effects. Always tell your doctor about every prescription, over-the-counter drug and herbal supplement you take.

Drug–Food Interactions: Ramditic DT can be taken with or without food. Alcohol may worsen dizziness or drowsiness and should be limited. There are no specific dietary restrictions, but take doses at the same times each day for steady control.

Drug–Disease Interactions: Patients with liver or kidney impairment may need dose adjustments. Caution is advised in people with cardiac conduction abnormalities, Brugada syndrome or other significant arrhythmias, in those with a history of serious drug rashes, and in individuals with depression or suicidal ideation who require close monitoring. During pregnancy, lamotrigine levels often fall; do not change doses without medical guidance your clinician may monitor blood levels and adjust. Always share your full medical history to ensure safe and effective use of Ramditic DT 50 mg and Ramditic DT 100 mg (lamotrigine dispersible tablets).