OXOTIC 300

OXOTIC 300

URSODEOXYCHOLIC ACID SUSTAINED RELEASE 300MG TABLET

OXOTIC 300 contains Ursodeoxycholic Acid (UDCA), a naturally occurring bile acid. It works by:

  • Reducing the production of cholesterol in the liver.
  • Decreasing cholesterol absorption from the intestines.
  • Breaking down cholesterol deposits in the bile and gallstones.
  • Improving the flow of bile in the liver and gallbladder, which helps reduce liver damage in certain chronic conditions.
This dual action dissolving cholesterol-rich gallstones and protecting liver cells makes it effective in managing both gallbladder and liver disorders.

OXOTIC 300 is prescribed to treat:

  • Cholesterol gallstones (in patients where surgery is not an option or needs to be avoided).
  • Primary biliary cholangitis (PBC) – a chronic liver disease where bile ducts are progressively destroyed.
  • Cholestatic liver diseases to improve bile flow and protect liver function.
  • Certain cases of liver damage due to bile stasis, including drug-induced or pregnancy-related cholestasis (if advised by a doctor).

  • Adults: The recommended dose is usually 8–10 mg per kg of body weight per day, given in divided doses or as sustained release tablets as prescribed by your physician.
  • For gallstone dissolution: Treatment may take several months (up to 6–24 months), depending on stone size and composition.
  • For primary biliary cholangitis: The dose and duration are long-term and must be individualized.
  • Always take the medicine exactly as prescribed by your doctor, preferably with food to improve absorption.
  • Do not stop treatment abruptly without medical advice.

OXOTIC 300 may interact with the following medicines:

  • Cholestyramine, colestipol, activated charcoal, or antacids containing aluminum → may reduce absorption of UDCA.
  • Ciclosporin → blood levels may increase, requiring monitoring.
  • Ciprofloxacin and dapsone → reduced effectiveness when taken together with UDCA.
  • Estrogen-containing medicines or oral contraceptives → may reduce the effectiveness of gallstone dissolution therapy.
  • Certain cholesterol-lowering drugs (fibrates, clofibrate) → may counteract the effect of UDCA.